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New York Giants at San Francisco 49ers 9/21/23 - NFL Betting Picks and Odds

Posted on 21 September 2023 by Cameron Ross

New York Giants vs. San Francisco 49ers

NFL: 8:15 PM EST

Sep. 21, 2023

TV: n/a
Latest Odds : SF -10 ; O/U 44.5


The New York Giants stay on the road Thursday night for a week 3 matchup in Santa Clara, CA against the San Francisco 49ers. New York comes into week 3 at an even 1-1 on the year following a heroic 20 one point comeback against the Arizona Cardinals. Offensively New York has been mediocre this season averaging 15.5 points on 333 yards per game. Defensively New York has been terrible giving up more than 320 yards and 34 points through two games played.

Quarterback Daniel Jones has been mediocre for New York this season completing 41 passes for 425 yards and two scores. Saquon Barkley is the top ball carrier on the roster with 114 yards on 29 carries, while quarterback Daniel Jones has 102 yards on 22 carries. Darren Waller is the top target in the New York offense this season with 9 receptions for 112 yards through two games played. Isaiah Hodgins and Saquon Barkley have combined for 14 total catches accumulating 105 yards and one touchdown each.

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The San Francisco 49ers will play their first home game of the season Thursday night undefeated through two games played. Offensively San Francisco is one of the best teams in football this year averaging nearly 390 yards after scoring 30 points in each of the first two games. The San Francisco defense has been mediocre having allowed 334.5 yards per game, but the 49ers have given up just 15 points across the first two outings.

Offensively San Francisco was the much better team against Los Angeles compiling 365 yards including 206 through the air. Defensively the 49ers had a few issues giving up nearly 390 yards but allowed just 23 points after forcing 2 turnovers in the game. Mr. Irrelevant Brock Purdy led the way for San Francisco completing 17 passes for 205 yards. Christian McCaffrey led all ball carriers in the game with 116 yards and one score on 20 carries.

Recent Betting Trends:

* NY Giants are 12-6 ATS in their last 18 games.

* NY Giants are 1-4 ATS in their last 5 games against San Francisco.

* NY Giants are 8-3 ATS in their last 11 games on the road.

* San Francisco are 10-3 ATS in their last 13 games.

* San Francisco are 14-1 SU in their last 15 games.

Free Betting Pick: San Francisco 49ers -10

The 49ers have been elite to start the year and will continue their dominance Thursday. San Francisco will dominate every aspect of this game against New York. Take the Niners Thursday to again roll to an easy win and cover. Final Score Prediction, San Francisco 49ers win and cover 31-10.

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